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| Pushpagiri Eye Institute |
(A Division of Pushpagiri Vitreo Retina Institute),
241, Uma Plaza Road No: 9, West Maredpally,
Secunderabad – 500 026
Andhra Pradesh , India
Ph No: 040-27804949/5959, 66328299/9299 |
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Basic Sciences
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To evaluate the retinal morphological alterations associated with fluorescein angiographic leakage in central serous chorioretinopathy (CSCR) using Fourier domain optical coherence tomography (FD-OCT)
Consecutive patients with clinical findings suggestive of CSCR underwent baseline fundus fluorescein angiography (FFA) and FD-OCT (raster and B-scan) of the fovea and FFA leakage sites. FD-OCT was repeated at monthly follow-up visits.
Twenty six eyes of 22 patients (four with bilateral involvement) were included in the study. FD-OCT showed a retinal pigment epithelial whereas (PED) corresponding to the FFA leak site in 18 (69%) eyes, whereas retinal pigment epithelial (RPE) irregularities and protrusions were noted in 8 (31%) eyes. Of these, four eyes with ill-defined angiographic leakage revealed discrete PEDs. Six eyes showed tethering of the outer retina at the site of a leaking PED. Granulated appearance of the outer retina was seen in 19 (73%) eyes of which 11 (58%) had subretinal precipitates and 8 (42%) had fibrin. Presence of either subretinal precipitates could not be correlated with the duration of detachment. Board area of RPE involvement adjacent to the leak site was seen in 11 (42%) eyes whereas RPE irregularities away from the leak site were noted in 14 (54%) eyes. Twelve (46%) eyes had single (n = 7) or multiple non- leaking PEDs, either in attached (n = 6) or detached retina (n = 7). In nine eyes having follow-up ranging upto 2 months, resolution of SRF was associated with collapse of PED (n = 3). Two eyes had persistence of PED and residual RPE irregularities (n = 4) and enlargement of PED (n = 3). Two eyes had persistence of PED with residual SRF.
Fourier domain OCT helps in precisely delineating the retinal pigment epithelial abnormalities and outer retinal alterations associated with CSCR. A larger area of involvement detected in eyes with focal angiographic leakage supports the view of widespread RPE pathology in CSCR.
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Chief Patron
H H Sri Vidya Nrusimha Bharathi
Shankaracharya of Pushpagiri Peetam.
Board of Directors |
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